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    Affymetrix Expression Console Software (v.1.0)

    Category  Genomics>Gene Expression Analysis/Profiling/Tools

    Abstract  The Affymetrix Expression Console Software provides signal
    estimation and Quality Control (QC) functionality for the GeneChip
    Expression Arrays (3’ Expression Arrays and Exon Arrays). It provides
    the ability to create summarized expression values (CHP files) for
    individual or collections of 3' Expression Array and Exon Array feature
    cell intensity (CEL) files.

    Note 1: The CHP file contains the analysis results from a Microarray
    Suite analysis (expression, CustomSeq, Genotyping...). The CEL (cell
    intensity) file contains only intensity information for a given probe on an
    array.

    In addition to CHP writing, the Expression Console Software also
    produces a collection of QC metrics for evaluating the success of
    hybridizations. The user defines thresholds for these metrics and the
    software highlights the metrics that do Not meet the defined
    thresholds. In addition, the CHP files are highlighted in the study table
    portion of the software, if they have any metrics outside of the defined
    thresholds.

    The Expression Console application contains graphic capabilities for
    visual inspection of the hybridization results.

    To identify outliers, the application is designed to display:
    1) Line graphs for individual or collections of metrics or probe sets
    2) Box plots for signal distributions before or after normalization
    3) MvA plots for signal distributions
    4) Heat maps for correlation matrices

    The Affymetrix Expression Console Software is targeted for research
    personnel (such as laboratory technicians, research associates, and
    scientists) analyzing Affymetrix GeneChip data.

    Note 2: The Expression Console application is Not a secondary gene
    expression analysis package. However, it does create the CHP files
    required for secondary gene expression analysis package(s) that can
    be selected from the Affymetrix GeneChip Compatible Program and/or
    other third party gene expression analysis packages.

    Note 3: See G6G Product Number 20072 for additional product info
    from this manufacturer.

    System Requirements  Microsoft Windows 2000 Professional with
    service pack 4.0 or Higher; Microsoft Windows XP with service pack 2.0
    or higher. The minimum hardware recommendations are: Memory
    (RAM): 1 GB*, Hard drive: 20 GB** (sufficient space should be available
    to meet user data requirements); Processor: 2.0 GHz Intel Pentium or
    higher.
    *Due to the large number of datapoints produced by the Exon Arrays, an
    additional 1GB of RAM is highly recommended.
    **The larger file sizes associated with Exon Array data should be taken
    into account when calculating the necessary free space requirement.

    Manufacturer   Home office; see web site for international locations.

    Affymetrix, Inc.,
    3420 Central Expressway
    Santa Clara, CA 95051
    Cust Service 888-DNA-CHIP (888-362-2447)
    Tel. 408-731-5000
    Fax. 408-731-5380
    sales@affymetrix.com
    support@affymetrix.com
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