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    GeneDirector 3.5

    Category  Genomics>Gene Expression Analysis/Profiling/Tools

    Abstract  GeneDirector 3.5 is an advanced comprehensive microarray
    information management system. It can be used as a central repository
    for all the data associated with array experiments and is designed to
    organize, retrieve, analyze, and query all of your microarray data.
    GeneDirector 3.5 provides an end-to-end solution for the microarray
    workflow process, starting from sample management and tracking,
    through automated image analysis and results generation. Every step
    of the microarray experimental process is modeled and allows you to
    be fully MIAME (Minimum Information About a Microarray Experiment)
    compliant. Product is built on a proprietary architecture that allows for
    flexible workflows to be defined, yet still enforce Standard Operating
    Procedures (SOP) and Protocols defined by your organization. With
    support for major industry platforms, and automated batch
    import/export features, GeneDirector 3.5 can be used to simplify
    operations and minimize technician error. GeneDirector 3.5 features
    include:

    Comprehensive & Customizable Workflow - 1) Unique Oracle database
    architecture allows for a flexible workflow; 2) On-Site configuration
    allows customization and modifications without the need for custom
    development; 3) Add unlimited number of properties to any field in the
    database without custom programming; 4) Properties can be any data
    type: numeric, text, image, or binary; 5) Enforce submission of key
    properties; 6) Enforce common vocabulary; 7) Define unlimited number
    of study types and factors for your experiments.

    Secure Collaboration - 1) Based on Oracle comprehensive security
    infrastructure; 2) Security change propagation and ownership transfer;
    3) Reader clients provide access to the database by anyone who has
    been provided with the permission and wants to retrieve data from
    GeneDirector; 4) All or any part of the data can be shared with
    individuals or groups; 5) Generation of Tab2MAGE file based on a
    GeneDirector project - allowing for submission to ArrayExpress data
    repository; 6) Multiple groups and administrators.
    Data Integrity - 1) You can review image analysis results directly from
    relationship viewer; 2) Manage data associated with array experiments;
    3) Enables you to store and backup data from a secure and centralized
    repository; 4) Complex custom queries can be constructed to search
    for specific information (such as, expression signatures) across the
    entire database; 5) Link Bioanalyzer data directly to RNA and amplified
    RNA data.

    Advanced Automation - 1) Batch import of Sample Information,
    Quantified Arrays, Scanned Arrays, Agilent Feature Extraction Files,
    Robust Multichip Analysis (RMA), Illumina BeadStudio and dChip data;
    2) Batch export native Affymetrix files; 3) Batch create sets of arrays,
    process multiple images, pre-process (normalize) data sets; 4) Batch
    import ImaGene data and automatically establish data relationships; 5)
    Automated Pre-Processing/Data Cleansing; 5) Robust, unsupervised,
    image processing for high-throughput environments.

    Platform Independence & Compatibility - 1) Direct integration with
    commercial microarray hardware platforms - Affymetrix, Agilent, Axon,
    PerkinElmer, Applied Precision, Genomic Solutions, etc: 2) Open
    architecture allows for integration with common equipment and
    software tools, such as, a) Agilent Bioanalyzer for RNA and amplified
    RNA (aRNA) data; b) Directly import Quality Control (QC) data from
    Tecan automated hybridization station; c) Directly import data from
    Affymetrix GCOS software; d) Directly import images and process from
    Agilent, Axon, and many other scanners; e) Directly import
    quantifications generated by Agilent, Affymetrix, RMA, etc; 3) Java
    Application Programming Interface (API) provided for customer's own
    development and integration; 4) Operating system independent - can
    run on Windows, Mac, and Linux; 5) Supports MIAME compliant data
    model for sharing and publishing data.

    Rapid & Dynamic Search Capability - 1) Can rapidly find any data
    through use of data organization, search, or linked association; 2)
    Project Summary can be reviewed, drill down and edit as required; 3)
    Comprehensive Search tool; 4) Keyword, General and Custom Query
    capability; 4) Relationship viewer - allows you to find information based
    on inherent relationships between array design, array type and
    samples, and experiment data; 5) Limit search scope by owner,
    project, date range, or data type.

    Full Affymetrix Support  - 1) Import from Affymetrix GeneChip Operating
    System (GCOS); 2) One Button import of all native Affymetrix files; 3)
    Store both raw data as well as processed quantifications - a) Raw data
    can be retrieved and reprocessed, b) Processed data can be used for
    analysis and mining.

    Enterprise Collaboration Capability - 1) Secure access allows
    individuals and groups to collaborate; 2) Project owner can assign
    work to various work groups; 3) Owner has full access; 4) Users can
    belong to more than one group within the system; 5) Flexibility in
    assigning projects; and more.

    System Requirements  

    Platforms Supported: Windows Win2k/WinXP/Vista, Linux, Mac OS X
    Database Supported: Oracle 10g
    Minimum: Pentium 4 or G4 1.0 GHz, 512MB RAM, 150 MB HD
    Recommended: Xeon or G5 2+ GHz, 2 GB RAM, 500 MB HD

    Manufacturer   Home office; see web site for international locations.

    BioDiscovery, Inc.
    2121 Rosecrans Ave., Suite 3315
    El Segundo, CA 90245
    Tel: (310) 414-8100
    Fax: (310) 414-8111
    support@biodiscovery.com
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