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    Rosetta Resolver System

    Category  Genomics>Gene Expression Analysis/Profiling/Tools

    Abstract  Rosetta Resolver System is an advanced gene expression
    data analysis system. The Resolver system provides a central
    analysis center and repository for biologists, statisticians, and
    bioinformaticians to evaluate gene expression data. The Rosetta
    Resolver system is now available in three (3) different configurations -
    Standard, Extended, and Premium - to scale with the size and needs of
    your organization.

    Products key features include:

    1) Data management and a data repository capable of growing with
    the research needs of your organization.

    2) Built-in, standardized analysis methods, as well as the ability to
    create new methods or access public methods. The technology-
    specific error models in the system enable you to identify differences in
    expression even when the number of replicates is small.

    3) Automated data import which enables you to quickly acquire
    expression data from multiple technologies, including those of
    Affymetrix, Agilent, Illumina, and GE Healthcare.

    4) An analysis environment which allows advanced users to create
    analysis workflows and templates for novice users.

    5) Easy data exchange between internal or external collaborators, as
    well as with the FDA.

    6) Support for data standards, such as CDISC/SEND (Clinical Data
    Interchange Standards Consortium/Standard for Exchange of
    Nonclinical Data) format. The system is also MIAME (Minimum
    Information About Microarray Experiments)-compliant.

    7) Ability to perform cross-species and/or cross-technology analyses
    [e.g., comparisons of Affymetrix versus Agilent arrays, or optionally,
    quantitative Polymerase Chain Reaction (qPCR) versus microarrays]
    see 'qPCR Module' info below.

    8) Support for 21 CFR Part 11, as validated by industry audits (see '21
    CFR Part 11' info below).

    qPCR Module -- The qPCR analysis module is an optional component
    available with the Resolver system. The module allows you to leverage
    the data management and analysis capabilities of the Resolver
    system to import, store, and analyze quantitative real-time polymerase
    chain reaction qPCR data.

    Specifically, the module includes:

    1) Validation of microarray results with cross-qPCR and microarray
    analysis.

    2) Ability to automate common qPCR analysis workflows.

    3) Direct import of relative quantity (RQ) and absolute quantity data
    (AQ) generated by Applied Biosystems (ABI) instruments.

    4) Specific quality control tools for qPCR analysis including
    visualizations of plate data.

    21 CFR Part 11 -- Rosetta Biosoftware has engineered the Resolver
    system with the necessary technical controls to enable customer
    compliance with 21 CFR Part 11.

    The Rosetta Resolver system provides:

    1) Audit Trail - Enable time-stamped audit trails to record the date and
    time of operator entries and actions that create, modify, or delete
    electronic records.

    2) Advanced Security - Configurable security protocols and authority
    checks allow regulation, management and audit of user access.

    3) Accurate and Complete Records - Archives raw data and associated
    metadata for retrieval.

    4) Electronic Signatures - With assistance from Rosetta Biosoftware's
    Professional Services group, enables user customization to adhere to
    electronic signature requirements.

    5) Documentation to Support Compliance - Comprehensive technical
    documentation that enables system operation in a manner consistent
    with the requirements set forth in the 21 CFR Part 11 regulations. And
    more.

    Note: The Rosetta Resolver system also offers an SDK - The Rosetta
    Resolver SDK (Software Development Kit) that enables you to tailor the
    Rosetta Resolver Gene Expression Data Analysis System to fit your
    research needs.

    System Requirements  Contact manufacturer

    Manufacturer   Home office

    Rosetta Biosoftware
    401 Terry Avenue N
    Seattle, WA 98109, U.S.A.
    Main: +1 206.926.1200
    Fax: +1 206.926.1299
    For general inquiries info@rosettabio.com
    For product information sales@rosettabio.com
    For Rosetta Resolver or Rosetta Elucidator system support:
    support@rosettabio.com

    Manufacturer's Web Site  www.rosettabio.
    com/products/resolver/default.htm

    Price  Contact manufacturer

    G6G Product Number   20088

    G6G Manufacturer Number  102303
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