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    CLC Combined Workbench

    Category  Cross-Omics>Sequence Analysis/Tools

    Abstract  CLC Combined Workbench creates a software environment
    enabling users to make a large number of advanced protein, DNA, and
    RNA sequence analysis, combined with smooth data management,
    and excellent graphical viewing and output options. CLC Combined
    Workbench includes all features and functions of CLC Free Workbench,
    CLC Protein Workbench, and CLC DNA Workbench, and CLC RNA
    Workbench. Product features a number of unique and innovative
    bioinformatics tools for supporting advanced biochemistry and
    molecular biology lab research.

    CLC Combined Workbench provides:

    1) Graphically and methodologically advanced bioinformatical tools for
    primer design, contig assembly and cloning vector design.
    2) A wide range of Protein and deoxyribonucleic acid (DNA) sequence
    analysis, including state-of-the-art graphical viewing and editing options.

    3) Advanced and fully integrated graphical editors for linear and 2D
    viewing and editing of ribonucleic acid (RNA) secondary structures and
    sequences.

    4) State-of-the-art algorithms for free energy minimization-based
    prediction of RNA secondary structure, including advanced options.
    5) Advanced tabular editor with full, integrated access to thermodynamic
    details of RNA structures.
    6) Detailed history log enabling tracking and documentation of all
    analysis and all modifying actions performed on a given set of data (e.g.
    on a protein sequence or on an alignment).
    7) Full integration of data management, bioinformatics analyses,
    reporting, and documentation of results. This eliminates time spent on
    manual data transfers between different programs and databases.

    8) Option of importing and working with external files such as Portable
    Document Format (PDF)-files, word processing files, and spreadsheet
    files directly from the workbench. All types of files related to a research
    project may thus be managed from one single application on your
    computer.
    9) A number of output functionalities, including printing and generation
    of graphics output in various file formats.
    10) User-defined view settings for consistent layout of graphics.
    11) Full integration with CLC Bioinformatics Cube and Cell, providing
    hardware accelerated database searches of high precision and high
    speed - up to 200 times faster than a laptop computer.
    12) Option of developing your own bioinformatics solutions using CLC
    Developer Kit.
    13) Sequence data, as well as calculations, search results, and files in
    external data formats are arranged in projects and can be saved locally
    on your desktop computer or stored on a shared network drive.

    Main bioinformatics features include:

    1) Editor for graphically and algorithmically advanced primer design.
    2) Integrated 3D structure viewer.
    3) State-of-the-art algorithms for free energy minimization-based
    prediction of RNA secondary structure, including advanced options.
    4) Advanced and fully integrated graphical editors for linear and 2D
    viewing and editing of RNA secondary structures and sequences.
    5) Advanced tabular editor with full, integrated access to thermodynamic
    details.
    6) Contig assembly and editing from chromatogram trace files and
    reference sequences.

    7) Integrated Basic Local Alignment Search Tool (BLAST) for Single
    Nucleotide Polymorphisms (SNPs) on database (db)SNP at National
    Center for Biotechnology Information (NCBI).

    8) Protein secondary structure prediction.
    9) Signal peptide prediction and localization (SignalP).
    10) Transmembrane helix prediction (TMHMM).
    11) Local Protein family database (Pfam) domain search.
    12) A graphically advanced cloning editor with total user control.

    13) Proteolytic cleavage site detection.
    14) Local and web-based BLAST, integrated with advanced viewing of
    search results.
    15) Discovery of protein patterns and DNA patterns.
    16) Motif search.
    17) DNA, RNA and protein sequence editor displaying both linear and
    circular molecules.
    18) DNA, RNA, and protein alignment editor.
    19) Manual annotation of sequences, including advanced editing and
    copying options.
    20) Reverse translation from protein to gene, based on translation
    tables from a number of species.
    21) Advanced restriction enzyme analysis and management.
    22) Dot plot based analysis.

    23) Integrated Public/Publisher Medical Literature Analysis and
    Retrieval System Online (PubMed) searches.
    24) Sequence logo graphs along DNA, RNA, and protein alignments.
    25) Simulation of restriction maps and virtual gels.

    System Requirements  

    System requirements for all workbenches from CLC bio

    Mac OS X 10.3 or later (including Intel-based Macs)
    Windows 2000, Windows XP, or Windows Vista
    Linux: Redhat or SuSE
    256 MB RAM required
    512 MB RAM recommended
    1024 x 768 display recommended

    Additional requirements for CLC Protein Workbench and CLC
    Combined Workbench

    3D viewing requires an OpenGL 3D graphics driver (included with
    almost all graphics cards)

    Java
    The CLC Free Workbench is built using Java technology, and requires
    that a Java Runtime Environment version 1.4 or newer is installed on
    your system.

    If you are a Windows or Linux user and do not have a Java Runtime
    installed you should choose an installer which include the JRE.
    Alternatively you can download and install a JRE from http://java.sun.
    com.

    Mac OS X includes a Java Runtime Environment as default.

    Manufacturer   Home office; see web site for international locations.

    CLC bio A/S
    Gustav Wieds Vej 10
    8000 Aarhus C
    Denmark

    VAT number
    DK 28 30 50 87

    Telephone
    Main:     +45 70 22 32 44       
    Sales:   +45 70 22 55 09        
    Fax: +45 70 22 55 19

    E-mail
    Main: info@clcbio.com
    Support: support@clcbio.com
    Sales: sales@clcbio.com

    Manufacturer's Web Site  www.clcbio.com/index.php?id=92

    Price   Contact manufacturer

    G6G Product Number  20096

    G6G Manufacturer Number 100520
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