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    Genesis Enterprise System Software version 3.0

    Category  Genomics>Gene Expression Analysis/Profiling/Tools

    Abstract  Genesis Enterprise System Software version 3.0 (Genesis
    3.0) provides a collaborative, secure environment incorporating
    integrated visualization and analysis tools that allow you to examine
    expression data and sample attributes simultaneously and perform a
    wide variety of analyses. This system enables you to create and
    manage a large number of sample and gene sets and store and share
    analysis results for on-going investigations.

    With Genesis 3.0, you can:

    1) View gene expression patterns across normal and diseased
    samples and study sets.

    2) Analyze patterns of differential gene expression in a diverse set of
    biological samples.

    3) Discover differentially expressed genes and potential biomarkers.

    4) Identify potential targets and mechanisms through pathway and
    ontology prioritization tools.

    Genesis 3.0 enables you to store, manage, and analyze large amounts
    of Affymetrix GeneChip array data and associated clinical, experimental,
    and genomic information. Designed and built as the delivery platform
    for Gene Logic's BioExpress and ToxExpress Systems, many
    pharmaceutical and biotechnology scientists use Genesis 3.0 to
    analyze genes and gene expression profiles as an integral part of their
    drug development programs.

    Key Features of the Genesis Enterprise System Software:

    1) Provides effective tools for simplified data analysis and pattern
    recognition using multiple options for filtering, reporting,
    transformations, and visual exploration of results via coordinated multi-
    pane viewers.
    2) Allows empirical analysis based on user-defined parameters.
    3) Enables the integration of gene attributes and sample details (e.g.
    clinical values) at the point of analysis. Integrated pathway analysis
    tools, expression data, clinical data, and reference data empower
    mechanistic analysis.
    4) Scripted analysis workflows can be easily created and sent to you by
    Gene Logic technical experts to meet your specific in silico research
    needs.

    Additional Features/Capabilities of the Genesis Enterprise System
    Software:

    Genesis Software Organizes and Interprets Your Gene Expression Data

    1) Sample set selection & management tools -- Create sets of samples
    to isolate and determine meaningful biological variables.
    2) e-Northern Reports -- Generate graphical displays of median and
    range of gene expression levels for a gene within specified sample
    sets.
    3) Human Chromosome View -- Visualize gene expression by mapping
    against genetic loci along a chromosome.
    4) Correlation Map (Heat Map) -- Use color to highlight similar or
    dissimilar correlation between the expressions observed in pairs of
    samples or pairs of genes in the result set.
    5) Principal Component Analysis (PCA) -- Reduce a matrix of
    expression data of many variables (genes) observed for a few
    experiments (samples) into a matrix of fewer variables (principal
    components) observed for the same experiments.

    6) Scatter Plot Viewers -- Plot numeric gene or sample data attributes
    against each other. Also provides for the visual correlation of genomics
    and classical observations.
    7) Pathway View -- Over 600 pathways from KEGG and exclusively
    provided by the Biocarta database for human and animal species.
    Pathways are fully integrated with gene expression data.
    8) Integration with Third Party Tools -- Direct integration with a number
    of leading third party analysis tools. Provides extensive import and
    export capabilities to support integrated analysis.
    9) Export data -- Analyze data using third-party software tools.
    10) Linkage and curated data extracts from various public and private
    sources of genomic information -- Develop a systems biology view of
    your gene(s) of interest.

    The GX Connect Module -- An advanced application for the import of
    Affymetrix GeneChip array, clinical, and experimental data into Genesis
    Software:

    1) An Extensible Markup Language (XML) interface facilitates software
    integration between GX Connect and your existing data repositories.

    2) Sample Data Editor allows direct entry of sample and donor
    descriptions, chemistry and laboratory values, clinical findings, and
    detailed pathology descriptions - over 1800 parameters are available.
    Extensible data model allows the definition of customer specific terms
    with full search and query support in analysis tools.

    3) GX Connect contains a full complement of automation and data
    management tools that scale from limited integration projects to high
    volume, enterprise applications.

    4) With GX Connect, you can create, manage, and mine your own
    reference database or add to BioExpress and ToxExpress Systems
    provided by Gene Logic.

    5) Allows side-by-side analysis of your sample data with Gene Logic
    content.

    Note: See G6G Product Number 20124 for additional product info from
    this manufacturer.

    System Requirements  

    Contact manufacturer

    Manufacturer   Home office; see web site for international locations.

    Gene Logic an Ocimum Biosolutions Company
    50 West Watkins Mill Road
    Gaithersburg, MD 20878
    Telephone: 301.987.1700
    Toll Free: 800.GENELOGIC (800.436.3564)
    Fax. 301.987.1701
    gxsupport@genelogic.com
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