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    ImaGene 8.0

    Category  Genomics>Gene Expression Analysis/Profiling/Tools

    Abstract  ImaGene 8.0 from BioDiscovery is a leading-edge microarray
    analysis software product that offers optimal performance with some of
    the broadest and most refined features available today. Through
    proprietary machine vision technology, ImaGene 8.0 delivers high
    quality data and advanced automation to quantify, normalize and
    analyze your microarray experiments.

    ImaGene 8.0 offers advanced features allowing you to rapidly explore
    the data from your microarray experiments with the highest level of
    confidence in its integrity. Products features/capabilities include:

    Most Advanced Automation --

    1) Spot Finding & Grid Placement - patented and efficient algorithms
    automatically thread a grid through each data point, performing
    thousands of calculations per second ensuring optimal placement and
    alignment.

    2) Spot & Array-Level Quality Control - ImaGene 8.0 will automatically
    analyze every spot and the array itself to determine the quality of the
    array image or individual spots, minimizing the need for laborious
    manual inspection of tens of thousands of spots, allowing users to
    have confidence in the reported measurements.

    Highest Quantification Accuracy --

    1) Patented Automated Segmentation - proprietary algorithms and
    processes are used to automate a precise segmentation process,
    discriminating between signal, background and contamination,
    ensuring the highest quality experimental data. This unique feature can
    even salvage contaminated spots by automatically removing artifacts
    that statistically do Not match the signal or background intensity profiles.

    One-Button Batch Processing --

    1) The optional batch-processing module enables rapid, completely
    hands-free processing of any number of images. This feature brings
    new efficiency to high-throughput environments where large numbers of
    arrays are processed each day. And, to keep check on workflow, an
    intuitive progress window shows you where you are along the way.

    Elegant Interface and Navigation --

    1) Easy to learn and use - ImaGene 8.0 continues a tradition of an
    intuitive design that is easy to learn to use and is similarly easy to
    navigate. With tabular formats and sliders, creating and managing
    settings is as simple as a click of a mouse.

    2) Interactive and integrated - with interactive and integrated tabular and
    graphical data views, ImaGene lets you see the correlations between
    images and related data with a wide variety of interactive plots
    (histogram, box, scatter, GenePie and M-A plots).

    Integrated Analysis Modules --

    1) Flexible options in ImaGene 8.0 can provide: multiple data
    normalization options including lowess on entire array; sub-grid or
    control spots; differential regulation analysis and visualization; direct
    integration with GeneSight-Lite for multiple array analysis; and
    statistical aCGH analysis and visualization.

    System Compatibility --

    1) ImaGene 8.0 is platform independent as it is available for Windows,
    MAC and Linux operating systems; is compatible with a broad variety of
    microarray types [staggered/orange packing, protein, array comparative
    genomic hybridization (aCGH), etc.] from a large number of
    manufacturers as well as home spotted arrays.

    Additional Features --

    1) Highly flexible in providing automated features requiring limited user
    interaction and manual features for asserting more user control when
    needed.

    2) Scanner independent – works with all scanners including Tecan,
    Agilent, GenePix (Axon), Perkin Elmer, Innopysis, and more.

    3) Ready to use templates for many commercial arrays including Agilent
    244K, 4x44K, 44K arrays.

    NEW in ImaGene 8.0 -- The new and improved features in ImaGene 8
    offer substantial performance improvement and higher quality allowing
    you to get to the results even faster.

    1) Improved auto-grid placement algorithm performing robust grid
    placement on even very dense and complex arrays.

    2) Support for multiple samples per array images such as Agilent’s
    4x44K array generating separate output files per field in the image.

    3) Improved auto-segmentation algorithm that removes speckle noise.

    4) Improved quantification processing time for largest arrays.

    Additional Data Analysis featues -- 1) Integrated data visualization tools
    in the core ImaGene application for quality, trend and regulation
    assessment; 2) Gene and condition partition manager; 3) K-means
    clustering; 4) Time series visualization; 5) Automated interface with web-
    based public genetic data.

    Optional --

    1) aCGH analysis and visualization module (See G6G Product Number
    20129).

    2) One-Button batch automation module.

    System Requirements  

    Platforms Supported: Windows 9x/Nt4/Win2k/WinXP, Linux, OS X
    Minimum: 700 MHz Pentium or G4, 256 MB RAM
    Recommended: 2.0 GHz or faster Core 2 Duo, 1024 or more MB RAM

    Manufacturer   Home office; see web site for international locations.

    BioDiscovery, Inc.
    2121 Rosecrans Ave., Suite 3315
    El Segundo, CA 90245
    Tel: (310) 414-8100
    Fax: (310) 414-8111
    support@biodiscovery.com

    Manufacturer's Web Site  www.biodiscovery.com/index/imagene

    Price   Contact manufacturer

    G6G Product Number  20128

    G6G Manufacturer Number 100431
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