SeqSolve™

Category Cross-Omics>Next Generation Sequence Analysis/Tools

Abstract SeqSolve™ is an advanced and user-friendly software solution for the tertiary analysis of Next Generation Sequencing (NGS) data.

By integrating state-of-the-art bioinformatics methods into one-click analysis workflows, SeqSolve is one of the only software products able to provide scientists with such a combination of both cutting edge and intuitive user experience.

Its Click And Go® technology enables the automatic processing of the data, which makes it simple to use for non-experts, along with a smart quality control system to prevent experimental biases.

SeqSolve results are therefore consistent, biologically relevant and reliable.

Starting from mapped reads as an input, SeqSolve performs a large portfolio of RNA-seq or ChIP-seq analyzes on any annotated genome, independently of the sequencing technology.

SeqSolve integrates state-of-the-art tools that are widely used by the NGS community and described in the scientific literature, including SAMtools, Cufflinks, MACS, and the IGV Genome Browser - (see G6G Abstract Number 20226).

Powered by the industry leading TIBCO® Spotfire® platform, SeqSolve displays scientific visualizations with real-time interactive charts that can be exported and into PowerPoint® or PDF reports in a simple click.

TIBCO® Spotfire® platform --

Spotfire provides Guided Analytic applications and services that empower users to make faster, more effective decisions. More than 30,000 users from 600 Global 2000 organizations gain insight with Spotfire products worldwide; in pharmaceuticals, high tech, manufacturing, oil & gas, consumer packaged goods, and academia.

The company maintains U.S. headquarters in Somerville, Massachusetts, and European headquarters in Goteborg, Sweden.

SeqSolve - The ultimate NGS data profiler --

Next Generation Sequencing (NGS) technology has led to novel breakthroughs at a significant pace. However, the amount of data that must be sifted through to reach a scientific conclusion makes the bioinformatics analysis highly challenging.

Integromics® addresses this problem by implementing its Click and GO® technology in the new SeqSolve software, allowing scientists to analyze NGS data in one click.

SeqSolve generates all the visualizations and statistical results needed for publication and may become the essential tool for your NGS data analysis.

SeqSolve Features and Capabilities:

CLICK and GO® Intuitive Workflows --

1) Fully automated data analysis in one click;

2) Pre-defined workflows ensure consistency across all analyzes and results;

3) User-friendly experience for biologists and non computational experts; and

4) Custom settings available for expert users.

Biologically Relevant Results --

1) Broad portfolio of RNA-seq and ChIP-seq tertiary (or downstream) analyzes;

2) Results include: read statistics and distributions, genomic coverage, global density profiles, differential expression, peak calling, alternative splicing, antisense transcription, new gene detection, and more;

3) Reveal the full landscape of your NGS data!

State-of-The-Art Methods --

1) Advanced statistics for comparative studies;

2) NGS-specific algorithms from the most recent scientific literature; and

3) Bring statistical significance to your results!

Smart Quality Controls --

1) Automatic monitoring of the results;

2) Advanced Quality Controls on strand specificity, library complexity, coverage bias, etc; and

3) Check for common experimental issues.

Real-Time Interactive Visualizations --

1) Dynamic and advanced graphics from the industry-leading TIBCO® Spotfire® platform; and

2) Includes the IGV Genome Browser.

Scientifically Validated --

1) Integromics published results from the SeqSolve methods in Cell and Nature publications are:

System Requirements

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Manufacturer

Manufacturer Web Site SeqSolve

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G6G Abstract Number 20101

G6G Manufacturer Number 101520