MetaBase

Category Cross-Omics>Pathway Knowledge Bases/Databases/Tools

Abstract MetaBase is the knowledge base (KB) behind MetaCore (see G6G Abstract Number 20024 for further info) and MetaDrug. Organized as an Oracle database with over 100 tables, MetaBase is one of the most comprehensive manually curated database of mammalian biology and medicinal chemistry data available today, in both industry and academia. Overall, it contains over 6 million experimental findings on protein-protein, protein-DNA and protein- compound interactions. Product also includes thousands of established signaling and metabolic pathways, ligand-receptor information for known drugs, drug targets and diseases, kinetic information on drug-metabolizing enzymes and relevant signaling proteins, ontologies for diseases, functional processes, toxicities, proteins and drugs.

GeneGo offers access to MetaBase tables and schema to a select group of large life science companies for pursuits in genomics, metabolomics, proteomics and more. Customers can integrate MetaBase content with their internal system and edit the interaction information or MetaBase can be used as their central repository for experimental data, integrate their own databases and algorithms and distribute enterprise wide within the organization. Product is installed behind the user’s firewall on a stand-alone server; No web access is available. Note: The product is made available at GeneGo’s discretion.

MetaBase provides customers with direct access to MetaCore and MetaDrug content -

• 1) It is one of the largest manually curated databases of the human “interactome”.
• 2) It is Oracle based and requires Oracle RDBMS 9.2 or higher.
• 3) Offers easy installation and update.

MetaBase contains data in the following categories -

Physical entities - 1) Genes; 2) Proteins; 3) Chemical compounds; 4) Enzymes.

Interaction data - 1) Signaling and Metabolic networks; 2) Chemical reactions.

Other data -

• 1) Different organism’s orthologs for human genes.
• 2) Gene and protein mappings to public identifiers.
• 3) Protein hierarchy, complexes, families.
• 4) Synonyms Diseases and annotations.
• 5) Cellular processes Proprietary GeneGo processes.
• 6) Canonical pathways and maps.
• 7) Tissues and localizations.

MetaBase enables research into proteomics, genomics, metabolomics and more through GeneGo's manually curated database of mammalian biology and medicinal chemistry.

System Requirements

Client (for web portal and in house installations):

• Internet Explorer 6.0 or higher is required
• Macromedia Flash 8 or higher Plug-In is required
• P4/Centrino/Core Duo CPU and 512MB of RAM is recommended

Server (for in house installations):

• 2 or more P4/XEON or AMD Opteron CPU’s with 4GB or more of RAM recommended
• SCSI HDD with minimum of 36 GB of storage is recommended
• RedHat Enterprise Linux 3, 4; SuSE 9.2; CentOS 4.4
• Development and X development packages installed
• JDK 1.4.2 (except 1.4.2_03) or later
• Oracle 9.2.0.6 or 10.2 DBMS and client tools, including imp/exp utilities
• MetaCore now supports x86-64 architecture

Manufacturer

• GeneGo, Inc.
• 500 Renaissance Drive, #106
• St. Joseph, MI 49085
• Tel: (888)592-3124
• Tel: (269) 983-7629
• Fax: (269) 983-7654
• customersupport@genego.com
• sales@genego.com

Manufacturer Web Site GeneGo, Inc.

Price Contact manufacturer.

G6G Abstract Number 20025

G6G Manufacturer Number 101109