Category Proteomics>Mass Spectrometry Analysis/Tools

Abstract BioTools™ provides support to mass spectrometry-based proteomics and protein analysis.

BioTools has been developed to translate mass spectral information into knowledge in both major approaches for proteomics and protein analysis: screening approaches generating high amounts of data and in-depth analysis of single or a low number of proteins, such as modifications, polymorphisms or splice variants.

Features of BioTools for automated protein identification via library search -

1) Protein identification as a batch process using matrix-assisted laser desorption/ionization-Time of Flight (MALDI-TOF) fingerprint, Protein Sequence Database (PSD) and complete liquid chromatography- tandem mass spectrometry (LC-MS/MS) data.

2) Search result judgement by Fuzzy Logic.

3) Batch result reporting, including visualization of MALDI-TOF results in MTP viewer format.

4) De-novo sequencing support.

Features of BioTools for protein structural analysis --

1) Seamless link of MS and MS/MS spectra and web-based library searches.

2) Automatic MS and MS/MS spectra annotation based on protein sequences.

3) Sequence handling with full support of cross-links and modifications.

4) Screening tools for post-translational modifications (PTMs).

5) Fine-structure characterization of proteins.

6) De-novo sequencing by RapiDeNovo module.

7) Mass Spectrometry-Basic Local Alignment Search Tool (MS-BLAST) homology search support.

BioTools Technical Data --

1) Support of flex™ series MALDI-TOF MS, esquire™ series ESI-Ion Trap MS, APEX™ FTMS, BioTOF™ ESI-TOF MS.

2) MASCOT (see G6G Abstract Number 20087) Intranet search software (Matrix Sciences, Ltd.) fully integrated.

3) Full support of proprietary databases in FASTA format.

4) Customer-specific modifications supported.

5) Copy and paste for spectra export.

Note: BioTools is designed for the interpretation of MS and MS/MS spectra of protein digests or peptides obtained with the full range of Bruker Daltonics ESI and MALDI instruments.

System Requirements

Runs on Windows NT4, Windows 2000 and Windows XP.


Manufacturer Web Site BioTools

Price Contact manufacturer.

G6G Abstract Number 20244

G6G Manufacturer Number 100442